Taste-Masked Actives

Actimask® Ibuprofen

Explore Actimask taste-masked ibuprofen for chewable and orally dispersible dosage forms. Review sensory performance, coating characteristics and release requirements together before moving into formulation trials.

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Actimask® Ibuprofen formulation and development Science in service of your next step.
Evaluate with purpose

A material choice
with your process in mind.

Review the product in the context of your intended application. Our team can help frame a focused technical conversation.

01

Set the sensory brief

Define the intended chewable or orally dispersible format and the sensory questions you want to evaluate.

02

Review formulation compatibility

Consider the coated material in the context of your active loading, excipient system and processing conditions.

03

Evaluate the complete product

Review sensory performance and release requirements together through your development and testing programme.

Material information

Grade & product details.

Review the product information below and discuss the specification relevant to your intended application.

Features

Benefits

Uniform Hydrogel Coating
  • Effective taste-mask prevents ibuprofen burning sensation
  • Smooth organoleptics in orodispersibles
  • No residual solvent

Rapid Drug Release
  • in vivo pharmacokinetics comparable to marketed products 
  • ODT meets compendial dissolution

High Assay
  • Provides formulating flexibility

Good Physical Characteristics
  • Easy to manufacture dose forms

Reputable Supplier
  • High quality and reliable supply

Bioavailable
  • Likely to be bioequivalent to marketed products
Technical documentation

Product information.

Request the technical documents relevant to your material, application and evaluation requirements.

Actimask Psb Oct 2017

Technical documentation

Improving The Solubility Of A Bcs Class Ll Drug Through Excipient Selection Application Data Sheet

Technical documentation
The wider portfolio

Continue your evaluation.

Product portfolio

Taste-masked actives

Explore taste-masked materials for chewable and orally dispersible dosage forms. Review sensory objectives alongside active compatibility, processing conditions and release requirements.

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Application expertise

Taste-masking

Address taste as part of your development strategy. Explore taste-masked materials and consider the interaction between sensory performance, active-ingredient characteristics and release requirements.

Explore details
Actimask® Ibuprofen
Actimask® Ibuprofen
Actimask® Ibuprofen
Actimask® Ibuprofen
Taste-Masking
Taste-Masking
Experience & expertise

Proven expertise. Established leadership.

Actimask Ibuprofen exhibits minimal drug release in the oral cavity during the first few minutes of exposure thus avoiding the unpleasant taste and sensation associated with this active when swallowed. However, at gastric pH it exceeds USP/EP compendial dissolution requirements. An in vivo pharmacokinetic study has showed that formulations with Actimask Ibuprofen are comparable to other marketed products.

Let’s move your thinking forward

A good formulation starts
with the right questions.

Tell us about your application. We’ll help you identify the material options and information worth exploring.

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